Name: Dehydroepiandrosterone powder,DHEA powder
Brand: Joyous Pellets Supplement raw materials, cosmetic ingredients, weight
Availability: InStock
Rating: 5 (1 reviews)

Dehydroepiandrosterone, DHEA is formed from 17α hydroxypregnenolone through the action of a 17-carbon chain enzyme. It is the precursor of androstenedione and testosterone. DHEA is the main androgen secreted by the adrenal cortex. In addition, a small amount of DHEA is also produced by the ovaries and testicles. Joyous' DHEA has two synthesis routes.

Product Name

dehydroepiandrosterone（DHEA）

Specification

99%

Appearance

white powder

CAS No

53-40-0

Detection method

By HPLC

Packaging

25kg cardboard drum

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Desciption

Product information
What is dehydroepiandrosterone powder?
Dehydroepiandrosterone, abbreviated as DHEA, chemical name is 3-β-hydroxyandroster-5-en-17-one, is a cholesterol △5,6 double bond and esterifiable 3-β-hydroxysteroid, its molecular formula It is C19H28O2, with a molecular weight of 288.41, a melting point Chemicalbook of 151°C to 153°C, and an optical rotation of +5.5°. It is an adrenal hormone precursor secreted by the reticular layer of the human adrenal cortex and has the functions of regulating obesity, preventing diabetes, resisting carcinogenesis and viral infection. It has physiological activities such as improving memory, immune response and stress response, and reducing tension. It is an intermediate in the production of steroid hormones and participates in the synthesis of adrenal glands to secrete a variety of hormones. It is produced from 17α-hydroxypregnenolone through the action of a 17-carbon chain enzyme. It is the precursor of androstenedione and testosterone. It is also produced in small amounts by the ovaries and testicles, and the secretion amount is about 25 mg per day for adults on average.
Joyous dehydroepiandrosterone powder specification

Terms	Standard	Terms	Standard
Product Name	dehydroepiandrosterone	Appearance	White powder
Assay	98%	Loss on Drying	≤2%
Total Heavy Metals	≤10 ppm	Ash	≤2%
As	≤0.5ppm	Total Plate Count	≤750 cfu/g
Pb	≤0.5ppm	Yeast and Mold	≤100 cfu/g
Cd	≤0.5ppm	Coliforms	Negative
Hg	≤0.1ppm	E.Coli	Negative
Packing	Pack in 25kgs paper-drums, inner by double plastic bag	Shelf life	24 months under the above condition, and in its original package

The role and market situation of dehydroepiandrosterone powder
1. Prevent and treat obesity DHEA has a thyroid-mimicking effect, which can inhibit food and fat intake, reduce fat accumulation, etc. Oral administration of small doses of DHEA sulfate has a certain effect on improving the amount and distribution of body fat and lowering blood lipids. In addition, DS can act on the mitochondrial respirator, inhibit food and fat intake, and is related to DHEA's resistance to glucocorticoids, which can prevent and treat obesity.
2. Anti-diabetic DHEA can improve glucose tolerance, increase insulin levels and have anti-diabetic effects. 3. Anti-cortical disease DHEA can enhance the activity of the endocrine system, reduce cortisol levels, and resist various pathological processes. Symptoms of patients with systemic lupus erythematosus (SLE) have been greatly improved after taking DHEA, indicating that DHEA has a certain effect in treating SLE disease. DHEA can help the body acquire cortical antibodies. The concentration of DHEA in plasma is closely related to various cortical diseases. The lower the concentration, the greater the risk of disease.
4. Anti-cancer DHEA has a certain effect in preventing and inhibiting tumor growth. First, it was clinically found that the anti-carcinogenic effect of DHEA is related to the reversal of breast cancer. Low levels of DHEA are associated with bladder and stomach cancer, independent of age. It has been confirmed that DHEA has protective and synergistic effects when used for tumor chemotherapy. Because DHEA has the effect of inhibiting ribose 5-phosphate, DHEA inhibits cancer by inhibiting excess mitochondria (NADPH) and ribose 5-phosphate. DHEA can inhibit the growth of pancreatic cancer cells. It is speculated that the mechanism is that DHEA inhibits the growth of pancreatic cancer cells by regulating the alternating changes in estrogen concentration in plasma.
5. Anti-aging effect: When a person is 25 to 30 years old, the DHEA content in the body is the highest. It will gradually decrease after the age of 30. The annual decline rate is about 2%. By the age of 70, the DHEA content in the body has dropped to its youthful level. was less than 25%; at the same time, the incidence of geriatric diseases related to the decrease in DHEA also increased. The decline in GnRH gene expression function leads to aging. It is believed that DHEA can restore the activity of GnRH neurons and prevent or improve some diseases related to the decline of DHEA by stimulating GnRH biosynthesis.
6. Immune response DHEA can restore damaged immune responses and improve the immune function of T cells and B cells. DHEA plays an important role in improving the physiological activity of insulin-like growth factor (IGF-1) and is a potentially beneficial drug for the treatment of immune deficiency.
7. Effect on bone quality DHEA itself cannot directly and independently affect the growth and differentiation of human osteoblasts, but it can achieve the growth and differentiation of osteoblasts by affecting the changes in 1,25-dihydroxyvitamin D3. The effectiveness of DHEA on bone quality depends on the form of sex hormones in bone cells and its endocrine effect on osteoblasts.
8. Protein metabolism DHEA is a protein anabolic hormone that promotes protein synthesis. According to studies by Marrero et al., feeding mice with DHEA (0.45%) can increase liver weight, increase liver mitochondria through liver protein induction, and restore RNA and protein synthesis.
9. In other aspects, DHEA has been extensively clinically studied in the treatment of menopausal syndrome, scleroderma, coronary heart disease, gout, psoriasis, AIDS, etc. The study also found that the pathogenic mechanism of tuberculosis cytoplasmic deformation is related to the concentrations of adrenocortical hormones and anti-adrenocortical hormones; the concentration of cortisol (Cortisol)/DHEA-S in fetal plasma is closely related to the delivery period.
There are two process routes for DHEA, one is the di-enolone route and the other is the 4AD route.
The price of 16DPA route is 230 USD/KG-260 USD/KG,
The price of the 4AD route is 170 USD/KG, which is the price of bulk goods.
There is basically no difference in the uses and effects of these two processes, but the production raw materials are different and the raw material costs are different.
16DPA is biologically extracted and then chemically synthesized, and 4AD is phytosterol fermentation and then chemically synthesized.
Some high-end users in Europe and the United States use 16DPA more, while less developed areas use 4AD more. European and American customers like the plant extraction process, and some customers think so. Most of the raw materials for sterols come from soybeans. Most of these soybeans come from South America and North America. There are genetically modified factors in the raw materials, which may affect European and American customers' rejection of sterol products.
Package and delivery

Delivery
1-80kg	80-300kg	More than 300kg
More suitable for express transportation, door-to-door	More suitable for air transportation,airport-to-airport	More suitable for ocean transportation,port-to-port
7-10 days for delivery time	3-4 days for delivery time	20-40 days for delivery time

What service we can provide
Joyous Health provides dehydroepiandrosterone powder OEM services. We can customize formulas for customers, private labels, capsules, tablets, soft capsules and sachets, low MOQ, which is suitable for direct sales by brands. Our OEM product shipping channels are stable and delivery times are fast and worthy of customers' trust, we have served more than 300 brands.

Joyous Health Factory information and certifications
Xi'an Joyous Health Biotechnology Co., Ltd. was established in 2011. Over the past 12 years, Joyous Health has obtained ISO 9001, FDA, ISO 22000, and GMP certifications.
Joyous Health has an advanced laboratory to control quality, so that each batch of products undergoes strict testing, and has professional R&D personnel to provide customized product services.
For more details please click here

Where to buy dehydroepiandrosterone powder?
We offer the best dehydroepiandrosterone powder at the most competitive price. dehydroepiandrosterone Powder bulk and wholesale powder have been 3rd lab-tested and verified for both product purity and identity.
We also provide dehydroepiandrosterone powder in bulk order or wholesale according to client needs. Just submit the requirements in the bottom form, we will reply soon!

Contacts: Faith Feng
Email:faith@joyouspellets.com
Tel and Whatsapp:+86 17391747738

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Contact: Xi'an international enterprise center B building, Fengcheng 4 road, Xi'an City, Shaanxi province, China; info@joyouspellets.com; +86 17391747738

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