Name: Pyridoxal5-phosphatemonohydrate powder,Pyridoxal Phosphate manufacturer
Brand: Joyous Pellets Supplement raw materials, cosmetic ingredients, weight
Availability: InStock
Rating: 5 (1 reviews)

The molecular formula of pyridoxal phosphate is C8H10NO6P, which is formed by the combination of vitamin B6 and phosphoric acid, including pyridoxal, pyridoxamine, and pyridoxine. It exists in the form of phosphate esters in the body. Among them, pyridoxal phosphate and pyridoxamine phosphate can transform into each other, and both are active forms.

Product Name

Pyridoxal5-phosphatemonohydrate

Appearance

Yellow powder

Specification

99%

CAS No

54-47-7,41468-25-1

Molecular Formula

C8H10NO6P

Package

25kg cardboard drum

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Desciption

Product information
What is Pyridoxal5-phosphatemonohydrate powder?
Pyridoxal Phosphate is also called Pyridoxal5-phosphatemonohydrate. Joyous’ product here is a monohydrate formed by the combination of vitamin B6 and phosphoric acid. CAS No. 41468-25-1. Pyridoxal Phosphate is slightly soluble in water and is soluble in ethanol, acetone, ether, and trichloride. Almost insoluble in methane.
Joyous Pyridoxal5-phosphatemonohydrate powder specification

Terms	Standard	Terms	Standard
Product Name	Pyridoxal5-phosphatemonohydrate	Appearance	Yellow powder
Assay	98%	Loss on Drying	≤2%
Total Heavy Metals	≤10 ppm	Ash	≤2%
As	≤0.5ppm	Total Plate Count	≤750 cfu/g
Pb	≤0.5ppm	Yeast and Mold	≤100 cfu/g
Cd	≤0.5ppm	Coliforms	Negative
Hg	≤0.1ppm	E.Coli	Negative
Packing	Pack in 25kgs paper-drums, inner by double plastic bag	Shelf life	24 months under the above condition, and in its original package

What are the functions of Pyridoxal5-phosphatemonohydrate?
The monohydrate form of Joyous is more stable. Functionally, pyridoxal phosphate is a coenzyme of transaminase and decarboxylase in amino acid metabolism. It can promote the decarboxylation of glutamic acid and increase the production of γ-aminobutyric acid, which is an inhibitor of Sexual neuroinhibitory transmitters can also be found in Joyous GABA products. Pyridoxal phosphate is a coenzyme of citrulline and ornithine.
As a coenzyme, pyridoxal phosphate acts as a coenzyme in all transamination reactions and in the decarboxylation and deamination reactions of some amino acids. A Schiff base bond (internal aldimine) is formed between the aldehyde group of pyridoxal phosphate and the ε-amino group of a specific lysine group in the aminotransferase. The α-amino group in the amino acid substrate replaces the ε-amino group of the active site lysine residue. The resulting external aldimine becomes deprotonated to form a quinoid intermediate, which in turn accepts a proton at a different position to form a ketimine. Ketimine is hydrolyzed to regenerate the amino group of the complex enzyme
Pyridoxal phosphate is a drug clinically used to treat Parkinson's syndrome. Promote the transamination of transaminase to increase the content of dopamine in the body. Usually covalently bound to the ε-amino group of the lysine residue in the active center of the aminotransferase.
PLP (Pyridoxal Phosphate) is the active form of vitamin B6. This vitamin mainly consists of three natural organic compounds: pyridoxal, pyridoxamine and pyridoxine. Several reactions catalyzed by pyridoxal phosphate include: transamination, α-decarboxylation, β-decarboxylation, β-elimination, γ-elimination, racemization and aldol reaction.
As a coenzyme, pyridoxal phosphate acts as a coenzyme in all transamination reactions and in the decarboxylation and deamination reactions of some amino acids. A Schiff base bond (internal aldimine) is formed between the aldehyde group of pyridoxal phosphate and the ε-amino group of a specific lysine group in the aminotransferase. The α-amino group in the amino acid substrate replaces the ε-amino group of the active site lysine residue. The resulting external aldimine becomes deprotonated to form a quinoid intermediate, which in turn accepts a proton at a different position to form a ketimine. The ketimine is hydrolyzed to regenerate the amino group of the complex enzyme.
In addition, pyridoxal phosphate is also a cofactor required for some transaminase enzymes that use unusual sugars (such as peroxyglycosamine and deoxyglycosamine) as substrates. In these reactions, pyridoxal phosphate reacts with glutamic acid, and the α-amino group of glutamic acid is transferred to pyridoxal phosphate to form pyridoxamine phosphate (PMP). Pyridoxamine phosphate then transfers its nitrogen to the sugar, forming an amino sugar.

The biochemical processes involved in pyridoxal phosphate include:
β-elimination reaction, such as the reaction completed by serine dehydratase and GDP-4-keto-6-deoxymannose-3-dehydratase (ColD) [3]
Condensation reaction in heme synthesis
dopa → dopamine
Excitatory transmitter glutamate → inhibitory transmitter γ-aminobutyric acid
S-adenosylmethionine (decarboxylation) → propylamine (one of the synthetic precursors of polyamines)
Histidine (decarboxylation) → histamine
It should be noted that pyridoxal phosphate does not participate in the transamination reaction in lysine catabolism.

Here is an atypical example:
Pyridoxal phosphate is also found in the liver on the enzyme glycogen phosphorylase, which degrades glycogen during glycogenolysis when signaled by glucagon or epinephrine. However, this enzyme does not utilize the active aldehyde group and instead utilizes the phosphate group on pyridoxal phosphate to function in the reaction.

Although most pyridoxal phosphate-dependent enzymes form an internal aldimine with pyridoxal phosphate via a lysine residue in the active site; some pyridoxal phosphate-dependent enzymes do not have this lysine residue, replaced by a histidine in the active site. This way, the histidine cannot form the internal aldimine, and thus the coenzyme cannot be covalently tethered to the enzyme. GDP-4-keto-6-deoxymannose-3-dehydratase (ColD) is an example of such an enzyme.
Package and delivery

Delivery
1-80kg	80-300kg	More than 300kg
More suitable for express transportation, door-to-door	More suitable for air transportation,airport-to-airport	More suitable for ocean transportation,port-to-port
7-10 days for delivery time	3-4 days for delivery time	20-40 days for delivery time

What service we can provide
Joyous Health provides Pyridoxal Phosphate powder OEM services. We can customize formulas for customers, private labels, capsules, tablets, soft capsules and sachets, low MOQ, which is suitable for direct sales by brands. Our OEM product shipping channels are stable and delivery times are fast and worthy of customers' trust, we have served more than 300 brands.

Joyous Health Factory information and certifications
Xi'an Joyous Health Biotechnology Co., Ltd. was established in 2011. Over the past 12 years, Joyous Health has obtained ISO 9001, FDA, ISO 22000, and GMP certifications.
Joyous Health has an advanced laboratory to control quality, so that each batch of products undergoes strict testing, and has professional R&D personnel to provide customized product services.
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Where to buy Pyridoxal Phosphate powder?
We offer the best Pyridoxal Phosphate powder at the most competitive price.Pyridoxal Phosphate Powder bulk and wholesale powder have been 3rd lab-tested and verified for both product purity and identity.
We also provide Pyridoxal Phosphate powder in bulk order or wholesale according to client needs. Just submit the requirements in the bottom form, we will reply soon!

Contacts: Faith Feng
Email:faith@joyouspellets.com
Tel and Whatsapp:+86 17391747738

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Contact: Xi'an international enterprise center B building, Fengcheng 4 road, Xi'an City, Shaanxi province, China; info@joyouspellets.com; +86 17391747738

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